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Ocular oncology

Intraocular Tumor Services

Imaging-led, multidisciplinary care for tumors arising within the eye or spreading to it from elsewhere in the body.

Fundus imaging and ultrasound examples of intraocular tumors
Clinical imagery from the Ocuprime archive

Intraocular tumors include primary tumors arising within the eye and secondary tumors that spread from another site. Early detection, multimodal imaging and coordinated management are important for protecting life, preserving the eye and retaining useful vision where possible.

Ocuprime provides diagnostic evaluation and evidence-based management led by ocular oncologist Dr. Sonal Yadav.

At a glance

Conditions and treatments

  • ✓Retinoblastoma
  • ✓Choroidal melanoma
  • ✓Choroidal metastasis
  • ✓Choroidal hemangioma
  • ✓Choroidal granuloma
  • ✓Optic nerve head melanocytoma
  • ✓Retinal pigment epithelial tumors

Retinoblastoma

Dedicated retinoblastoma programme →

Read Ocuprime's parent-focused guide to warning signs, examination, treatment, genetic counselling and follow-up.

Overview

The most common primary intraocular malignancy of childhood, often presenting with a white pupillary reflex or strabismus.

Evaluation

Examination under anesthesia, fundus photography, ultrasonography and MRI support classification and treatment planning.

Treatment

Care may combine systemic or targeted chemotherapy with focal laser, cryotherapy or thermotherapy. Advanced, non-salvageable eyes may require enucleation followed by implant and prosthetic rehabilitation.

Choroidal melanoma

Overview

The most common primary intraocular malignancy in adults, arising from melanocytes in the uveal tract.

Evaluation and treatment

Ultrasound, autofluorescence and enhanced-depth OCT define the lesion and risk features. Treatment planning may include plaque radiotherapy co-management, thermotherapy or enucleation, together with systemic surveillance.

Choroidal metastasis

Overview

Secondary tumors in the choroid most often originate from systemic cancer, including breast or lung cancer.

Our approach

Multimodal imaging and, when necessary, fine-needle aspiration assist diagnosis. Treatment is coordinated with oncology and may involve systemic therapy or radiotherapy.

Choroidal hemangioma

Overview

A benign vascular tumor that may impair vision through subretinal fluid or macular edema.

Our approach

Angiography, OCT and ultrasound guide observation or treatment such as photodynamic therapy, thermotherapy or radiotherapy in selected cases.

Choroidal granuloma

Overview

Inflammatory or infectious lesions associated with conditions such as tuberculosis or sarcoidosis can mimic a tumor.

Our approach

Imaging and systemic investigation identify the cause so antimicrobial or immunomodulatory treatment can be directed appropriately.

Optic nerve head melanocytoma

Overview

A usually benign, deeply pigmented lesion of the optic disc that can rarely grow or cause local complications.

Our approach

Baseline photography, OCT and ultrasonography allow long-term surveillance and help distinguish stability from transformation.

Retinal pigment epithelial tumors

Overview

Rare lesions range from benign congenital hypertrophy or adenoma to malignant adenocarcinoma.

Our approach

OCT, autofluorescence and angiography support diagnosis. Stable benign lesions may be observed; progressive lesions are considered for local treatment or surgery.

Academic references and authored works

  1. Yadav SP, Tomar AS, Finger PT, Gallie B. Local Chemotherapy for Intraocular Tumors. In Surgical Ophthalmic Oncology: A Collaborative Open Access Reference. ↗
  2. Yadav SP (Editor). Retinoblastoma: Diagnosis to Management. Nova Science Publishers. ↗
  3. Yadav SP, Tomar AS, Finger PT. Topical Chemotherapy for Ocular Tumors. In Surgical Ophthalmic Oncology.
Explore all publications →

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